|2.||Cell and Molecular Biology|
|3.||Stem Cell Biology & Regenerative Medicine|
The Kaldis laboratory studies how cell division is coupled to metabolism and how these two pathways talk to each other. We use genomics, metabolomics, proteomics, genetics, cell biology, and biochemistry tools to investigate how these processes are regulated in vivo; specifically in mice. Our largest project deals with liver regeneration and liver cancer where we focus on how cell division affects differentiation and metabolism. In addition, we also study how cyclin-dependent kinases (Cdks) regulate biogenesis and meiosis in male germ cells.